Using !commercial command in Nightbot
Nightbot !commercial Command

Fill the space of a stream while also earning ad revenue.

So you have to use the bathroom or answer that call?  If you have Nightbot (https://nightbot.tv) and streaming on Twitch.  Just type in !commercial in the chat.  This will let Twitch know to run an ad if one is available.   The number after the command is an interval of 30.  Ad runs can be from 30 secs to 3 mins.   Your moderators can issue this command. 

Examples

!commercial 30
!commercial 90

Bonus: Learn how to use the Shoutout command in Nightbot.